Change Of Urinary Fluoride And Bone Metabolism Indicators In The Endemic Fluorosis Areas Of Southern China After Supplying Low Fluoride Public Water by Shaoxian Chen, Boling Li, Shao Lin, Yixiang Huang, Xinhua Zhao, Min Zhang, Yuan Xia, Xiaoheng Fang, Junyi Wang, Syni-An Hwang and Shouyi Yu

Few studies have evaluated health impacts, especially biomarker changes, following implementation

of a new environmental policy. This study examined changes in water fluoride, urinary fluoride (UF), and bone metabolism indicators in children after supplying low fluoride public water in endemic fluorosis areas of Southern China. We also assessed the relationship between UF and serum osteocalcin (BGP), calcitonin (CT), alkaline phosphatase (ALP), and bone mineral density to identify the most sensitive bone metabolism indicators related to fluoride exposure.

Link :http://download.springer.com/static/pdf/772/art%253A10.1186%252F1471-2458-13-156.pdf?originUrl=http%3A%2F%2Fbmcpublichealth.biomedcentral.com%2Farticle%2F10.1186%2F1471-2458-13-156&token2=exp=1461751735~acl=%2Fstatic%2Fpdf%2F772%2Fart%25253A10.1186%25252F1471-2458-13-156.pdf*~hmac=36a10673a6fd835c55ac353781767411ee50a212c6ea9453fa35958051dc6d8b